A CROSS SECTIONAL STUDY ON PLATELET COUNT/ SPLENIC DIAMETER RATIO AS NON INVASIVE PREDICTORS OF ESOPHAGEAL VARICES IN CIRRHOTIC PATIENTS
Author:
Ahmed Syed1, Tejaswini R.N.2, Viquaruddin Hamza Mohammed3, Khizer Mohammed4, Khaliq Abdul5, Siddiqua Ayesha6
Affiliation:
1. SeniorResident,DepartmentofMedicine,ApolloMedicalCollege,Hyderabad 2. Assistant Professor, Department of Medicine, Apollo Medical College, Hyderabad. 3. Medicine Registrar 4. Junior Resident, Department of Gastroenterology ESIC Medical College, Hyderabad. 5. ConsultantGastroenterologist&Hepatologist,HealthINNClinic,Hyderabad. 6. Medical Ofcer, TSRTC Hospital, Hyderabad.
Abstract
Portal hypertension commonly accompanies the presence of liver cirrhosis, and the development of
esophageal varices is one of the major complications of portal hypertension. The development of
esophageal varices is the most serious consequence of portal hypertension due to the risk of rupture and variceal hemorrhage.
All patients in the study were evaluated with detailed history and full clinical prole. They underwent hematological and
biochemical tests, like liver function tests, complete blood counts, renal function tests, prothrombin time, Ultrasonography of the
abdomen to conrm the presence of cirrhosis and to record the spleen bipolar diameter, portal vein size and ascites. Upper GI
endoscopy was done in all patients to conrm the presence of varices and also to grade them accordingly. The ROC curve was
applied to determine the cut-off values with the best sensitivities and specicities for all the three variables. A cut-off value of
1014 was obtained for platelet count to spleen diameter ratio, which gave a sensitivity of 84.31% and a specicity of 75.00 %.
Publisher
World Wide Journals
Subject
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