TAMSULOSIN VS TOLTERODINE IN THE MANAGEMENT OF URETERIC STENT RELATED SYMPTOMS FOLLOWING URETERORENOSCOPY

Abstract

Background: Indwelling ureteric stents produce varying degrees of complication and discomforts ranging from frequency and urgency to haematuria or infection and signicantly impacts quality of life. Aim: assess the effectiveness of Tamsulosin and tolterodine in improving the lower urinary tract symptoms of patients with indwelling double –J- ureteric stents following ureterorenoscopy Methods: The study was conducted in randomized, double-blind manner in department of general surgery , NMCH ,Patna from 1st January 2014 to 10th June 2015. In total, 40 patients with double J stent were randomly divided into two groups (group A, n: 20, group B, n: 20 ). Each patient randomly received one pack of drug in different colours of the content to take Tamsulosin 0.4 mg before sleep, Tolterodine 4 mg once a day : group A received Tolterodine , group 2 Tamsulosin a for 1 month in a double-blind manner. Ureteral stent-related morbidity indices which analysed included urinary symptom, pain, general health, quality of work and sex scores were measured by Ureteral Symptom Score Questionnaire for rst and fourth weeks after drug consumption and the rst week after double J stent removal. Results: No signicant change in various domains of USSQ like urinary symptoms , body pain, general health , work performance , sexual matters. Conclusions: Both drugs minimise the symptoms however a larger well-designed study needs to be conducted to conrm the ndings.