CLINICAL OUTCOME OF TRAUMATIC BRAIN INJURIES IN PATIENTS WITH SICKLE CELL DISEASE: A TERTIARY CARE EXPERIENCE AND REVIEW OF LITERATURE.

Author:

Modi Mehul1,Mahantshetti Prakash2,Gandhi Purvi3,Sali Vihang4

Affiliation:

1. MS, Mch (Neurosurgery), Associate Professor, Department of Neurosurgery, Government Medical College, Surat

2. MS, Mch (Neurosurgery), Associate Professor, Department of Neurosurgery, JNMC, Belagavi, Karnataka

3. MD(Microbiology), Clinical Tutor, Department of Microbiology, Government Medical College, Surat

4. MS, Mch(Neurosurgery), Consultant Neurosurgeon, Department of Neurosurgery, Government Medical College, Surat.

Abstract

Sickle cell disease (SCD) is a hereditary blood disorder characterised by an abnormality in the oxygen carrying capacity of haemoglobin molecule in red blood cells. WHO has recognised 14 communities in South Gujarat amongst the tribal groups with high prevalence of SCD. Traumatic brain injuries (TBI) can lead to increased secondary damage due to presence of hypoxia and hypotension; which are worsened in the presence of SCD leading to grave outcomes. In one of this rare kind of study; 11 patients of TBI with SCD were analysed. 5(45.45%) patients had history of no trauma or minor trauma with a mortality of 3(27.27%) patients out of 11. All (100%) patients had hypoxia and hypotension at the time of presentation. Aresearch on bigger scale is needed to identify specic interventions that may improve outcomes in this population.

Publisher

World Wide Journals

Subject

Economics and Econometrics,Education,Earth-Surface Processes,Geography, Planning and Development,Clinical Biochemistry,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Chemistry,Linguistics and Language,Language and Linguistics,General Medicine,Computer Science Applications,Linguistics and Language,Education,Language and Linguistics,History,Cultural Studies,Physiology,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,Cultural Studies

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