CHANGING PATTERN OF HAEMOGLOBIN LEVEL FOLLOWING ANTI-MALARIAL TREATMENT AMONG MALARIA CASES ATTENDING A TERTIARY CARE HOSPITAL IN KOLKATA

Abstract

Anaemia is one of the major causes of severe and complicated malaria. Malaria associated anaemia are due to decreased production of RBCs and lysis of infected and uninfected erythrocytes. The role of anti-malarial treatment in correcting anaemia are not studied extensively. The present work was undertaken to study the changing pattern of haemoglobin level following anti-malarial therapy. A total of 201 microscopically positive mono-infected with P. vivax (103) and P falciparum (98) patients were recruited and treated with antimalarial drugs and followed up on day 3, 14, and 28 to study the changing pattern of haemoglobin level. Among the P. falciparum positive patients mean haemoglobin level on Day 0 and day 28 was 13.17 g/dl and 13.31 g/dl whereas among P. vivax cases mean haemoglobin level was 13.28 g/dl and 13.29g/dl, respectively. Among the P. falciparum cases (n = 98), 4.08%, 16.33% and 79.59% was classied as moderate anaemia, mild anaemia and normal, respectively. Similarly, among the P. vivax cases (n = 103), 1.94%, 17.47% and 80.58% had moderate anaemia, mild anaemia and normal, respectively. Mean haemoglobin level was declined on day 3 which gradually increased to its initial level by day 28 among both P. falciparum and P. vivax cases. Similar study in other malaria endemic areas will be helpful for better understanding the changing pattern of haemoglobin level among malaria patients.