A STUDY ON CLINICAL PROFILE AND LABORATORY PROFILE CHANGES OF ENTERIC FEVER

Author:

Chandra Das Krushna1,Jana Debarshi2

Affiliation:

1. M.B.B.S, M.D, (PAEDIATRICS), Consultant paediatrician.

2. Young scientist, IPGMER and SSKM Hospital, Kolkata.

Abstract

AIM:The aim of the study is to asses study the clinical and laboratory prole. Culture positive & sensitivity pattern of Salmonella enteric and its response to antimicrobial therapy admitted in SSKM Hospital in Kolkata. MATERIAL AND METHOD: This is a prospective, observational study of paediatric aged between 5-12 years who are admitted in SSKM Hospital in Kolkata, West Bengal, India during the period of Sep 2016- Sep2018 the study includes 104 pediatric who were suffering from Enteric fever.RESULT:We found that 22(21.2%) patients had lymphadenopathy, 83(79.8%) patients had positive widal test (O antigen), 18(17.3%) patients had positive widal test (H antigen) and 42(40.4%) patients had positive blood culture. According to blood culture, 5(4.8%) patients had S.para typhi and 36(34.6%) patients had S.typhi. CONCLUSION: Leucopenia, eosinopenia and mildly elevated liver enzymes are common laboratory ndings. Widal is though a good screening test but has poor specicity for diagnosing culture positive enteric fever cases.

Publisher

World Wide Journals

Reference13 articles.

1. Mohanty S, Gaind R, Sehgal R, Chellani H, Deb M Neonatal sepsis due to Salmonella typhi and Paratyphi a. J Infect Dev Ctries. 2009;3:633-8.

2. Karande SC, Desai MS, Jain MK Typhoid fever in a 7 month old infant. J Postgrad Med. 1995;41:108-9.

3. Olutola PS, Familusi JB. Salmonella typhi pneumonia without gastrointestinal manifestations. Diagn Imaging Clin Med. 1985;54:263-7.

4. Crump JA, Mintz ED. Global trends in typhoid and paratyphoid fever. Clin Infectious Dis. 2010;50:241.

5. WHO Background document. Communicable disease surveillance and response vaccines and biologicals: The diagnosis, treatment and prevention of typhoid fever 2003. WHO/V &/B/03.70.

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