A STUDY ON PREVALENCE OF HELICOBACTER PYLORI IN BLEEDING PEPTIC ULCER USING RAPID UREASE TEST

Author:

M N Lokesh1,K N Anil Kumar2,M Madan3

Affiliation:

1. Associate Professor, Department of Surgery, BGS Global Institute of Medical Sciences, Bangalore, Karnataka.

2. Assistant Professor, Department of Surgery, BGS Global Institute of Medical Sciences, Bangalore, Karnataka.

3. Professor, Department of Surgery, BGS Global Institute of Medical Sciences, Bangalore, Karnataka.

Abstract

BACKGROUND: Helicobacter pylori (H. pylori) is the leading cause of peptic ulcer disease in India. Timely diagnosis and proper treatment is required for the eradication of H. pylori infection and prevention of its associated complications. AIMS AND OBJECTIVES: This study aims to evaluate the prevalence of H. pylori infection in patients presenting with bleeding peptic ulcer. MATERIAL AND METHODS: This is prospective study conducted from January 2019 till January 2021 in patients with bleeding peptic ulcer admitted at BGS Global Institute of Medical Sciences. All the patients under went endoscopy and biopsy was taken from Antral region for Rapid Urease Test. RESULT: 164 patients were included in the study with duodenal ulcer bleeding in 129 (78.6%) patients, gastric ulcer in 30 (18.3%) patients and both gastric and duodenal ulcer in 5 (3.1%) patients. Positivity for RUT was seen in 147 patients (89.6%). CONCLUSION: Early intervention in the patients with peptic ulcer disease in the form of endoscopic biopsy will help in prevention of recurrent bleeding episodes and other associated complications.

Publisher

World Wide Journals

Reference9 articles.

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2. Ozbek, A. (2010, July). Can Helicobacter pylori invade human gastric mucosa?: an in vivo study using electron microscopy, immunohistochemical methods, and real-time polymerase chain reaction. PubMed. https://pubmed.ncbi.nlm.nih.gov/19904218/

3. Prasad, S. (1994). Prevalence of Helicobacter pylori in southern Indian controls and patients with gastroduodenal disease. PubMed. https://pubmed.ncbi.nlm.nih.gov/7827302/#:%7E:text=various%20gastroduodenal%20diseases.-,H.,%25)%20with%20non%2Dulcer%20dyspepsia.

4. Duck, W. M. (2004, June). Antimicrobial resistance incidence and risk factors among Helicobacter pylori-infected persons, United States. PubMed. https://pubmed.ncbi.nlm.nih.gov/15207062/

5. Malfertheiner, P. (2006). Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. PubMed. https://pubmed.ncbi.nlm.nih.gov/17170018/

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