STUDY OF THE EFFICACY AND SUCCESS RATE OF MIFEPRISTONE AND MISOPROSTOL V/S MISOPROSTOL ALONE IN MID-TRIMESTER ABORTION-Reference-Cited by-同舟云学术

STUDY OF THE EFFICACY AND SUCCESS RATE OF MIFEPRISTONE AND MISOPROSTOL V/S MISOPROSTOL ALONE IN MID-TRIMESTER ABORTION

Published:2021-01-01 Issue: Volume: Page:1-3
ISSN:
Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
language:en
Short-container-title:IJAR

Author:

Das Karuna Kanta¹,Dutta Bijoy Kumar¹,Gogoi Chintumoni²

Affiliation:

1. Associate Professor, Obstetrics and Gynaecology department, Gauhati medical college and Hospital, Guwahati, Assam, India.

2. Post Graduate Trainee, Obstetrics and Gynaecology department, Gauhati medical college and Hospital, Guwahati, Assam, India.

Abstract

Objective- To compare the relative efficacy and success rate of combination of mifepristone and misoprostol with misoprostol alone in mid-trimester abortion by correlating induction abortion interval (IAI) between two study groups. Methods- A comparative study was carried out by dividing 100 women seeking for abortion into two groups (50 each). GroupA received 200mg mifepristone orally followed by 600mcg misoprostol vaginally (24 hours later) which was repeated 4 hourly by 400mcg sublingual misoprostol upto a maximum of 5 doses. GroupB received 600mcg misoprostol vaginally and dose was repeated 4 hourly by 400mcg of misoprostol sublingually. Result- the success rate in GroupA was 100%, whereas in Group B was 94%. The mean IAI in GroupA was lesser (10.8 hours) as compared to GroupB (13.5 hours) p value 0.01. The mean dose of misoprostol in GroupA was 1400mcg compared to GroupB 1760mcg (p value 0.0001). Conclusion- Pre-treatment with mifepristone significantly shortens the IAI and increase the successful abortion rate.

Publisher

World Wide Journals

Reference13 articles.

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