ROLE OF TUMOR MARKERS IN THE DIAGNOSIS OF MALIGNANT PLEURAL EFFUSIONS

Author:

Kandi Subhakar1,P Ajay Kumar1,Kandi Shravika Reddy2

Affiliation:

1. Department of Pulmonary Medicine, Osmania Medical College, Hyderabad, India.

2. Malla Reddy Institute of Medical Sciences, Hyderabad.

Abstract

As an aid in the differential diagnosis of oxidative pleural effusions tumor markers were investigated. We measured carcinoembrionic antigen (CEA) and a glycoprotein CA 15-3 in the pleural fluid of 33 patients with carcinomatous pleural effusions and of ten patients with tuberculous pleurisy and other causes because we have frequently found those diseases to be associated with exudative pleuritis. CEA and CA 15-3 were significantly higher in carcinomatous pleural fluids than in tuberculous fluids (p value of 0.0287), therefore combined assay of CEA and CA 15-3 may be useful in distinguishing pleural effusions due to malignancies from those of tuberculous origin.

Publisher

World Wide Journals

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