UNCOMMON OBSERVATION OF CHIASMATIC SARCOIDOSIS MIMICKING A PSEUDOTUMOR LESION-Reference-Cited by-同舟云学术

UNCOMMON OBSERVATION OF CHIASMATIC SARCOIDOSIS MIMICKING A PSEUDOTUMOR LESION

Published:2021-07-01 Issue: Volume: Page:87-88
ISSN:
Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
language:en
Short-container-title:IJAR

Author:

Ahizoune Aziz¹,Bourazza Ahmed²

Affiliation:

1. Specialist In Neurology Department Of Neurology And Neurophysiology, Mohammed V Military Teaching Hospital, University Of King Mohammed V-souissi, Rabat,Morocco.

2. Professor And Unit Head Department Of Neurology And Neurophysiology, Mohammed V Military Teaching Hospital, University Of King Mohammed V-souissi, Rabat, Morocco.

Abstract

Sarcoidosis is a chronic multisystem disease characterized histologically by the accumulation of noncaseating epithelioid granulomas in the affected tissues. Chiasmatic sarcoidosis is rarely reported and presents a problem of differential diagnosis especially with gliomas and meningiomas. A 27-year-old patient with no previous pathological history presented with painless bilateral visual disturbances predominantly on the left, which rapidly progressed with moderate headaches over two months ago. Humphrey visual eld study showed bilateral inferotemporal quadranopsia. Brain MRI showed an inammatory aspect with thickening of the optic chiasm. Investigations studies revealed an elevated angiotensin-converting enzyme associated with hilar and mediastinal adenopathies. Histological study of the labial biopsy demonstrated sarcoid granulomas. Involvement of the optic chiasm by sarcoid granulomas has been reported in the literature and is most often misdiagnosed as gliomas or meningiomas,

Publisher

World Wide Journals

Reference10 articles.

1. Murphy OC, Krumholz A, Stern BJ. Sarcoidosis of the Nervous System. In: Aminoff’s Neurology and General Medicine. Elsevier, pp. 867–884.

2. Fritz D, van de Beek D, Brouwer MC. Clinical features, treatment and outcome in neurosarcoidosis: systematic review and meta-analysis. BMC Neurol 2016; 16: 220.

3. Ng KL, McDermott N, Romanowski CA, et al. Neurosarcoidosis masquerading as glioma of the optic chiasm in a child. Postgrad Med J 1995; 71: 265–268.

4. Touzé R, Bremond-Gignac D, Robert MP. Syndrome chiasmatique. J Fr Ophtalmol 2021; 44: 84–98.

5. Suresh S, Kosmorsky GS, Lee MS. Isolated optic nerve sarcoidosis. 5.