Affiliation:
1. Associate Professor of Smt kashibai Navale Medical college Pune
Abstract
Background: In high risk pregnancies with poor fetal outcome careful examination of placenta along
with microscopic study may frequently point to the cause of perinatal death. So we have planned a
prospective observational study was to illustrate the gross and microscopic changes in placenta in certain normal and
abnormal pregnancies and to analyses the relationship of placental pathology with fetal outcome. A p Methods: rospective
study of 100 deliveries at a tertiary teaching hospital in India. Each placenta was studied macroscopically in labour room and
sent for microscopic examination. The study included placentas of normal pregnancies and those with high-risk pregnancies.
Microscopically placentas were studied for vessel wall thickening, infarction, villitis, chorioangiosis, calcication and
intervillous hemorrhage. The outcome variables were studied in each histological group and compared with the normal group
using Ψ2 test for homogeneity. For cell frequencies less than 5, Fischer Exact Test was used. Vess Results: el wall thickening was
demonstrated in 51% patients. Infarcts were demonstrated in 14%. Placental abnormalities Conclusions: like vessel wall
thickening, and infarction is associated with abnormal fetal and neonatal outcome.
Subject
Paleontology,Stratigraphy,Geology,Building and Construction,Architecture,Human Factors and Ergonomics,Orthopedics and Sports Medicine,Industrial and Manufacturing Engineering,Polymers and Plastics,Mechanical Engineering,Mechanics of Materials,Civil and Structural Engineering,General Physics and Astronomy,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,Psychiatry and Mental health,Clinical Psychology,Development,Geography, Planning and Development,Health Policy,Economics, Econometrics and Finance (miscellaneous),Literature and Literary Theory,Linguistics and Language
Reference16 articles.
1. Altshuler G, Deppisch LM. College of American pathologist’s conference XIX on the examination of the placenta. Report of the working group on indications of placental examination. CAP placenta consensus conference. Arch Pathol Lab Med. 1991;115;701-3.
2. Benirschke K, Kaufmann P, Baergen R. Pathology of the Human Placenta. 5th ed. New York, Springer Verlag; 2012.
3. Fox GE, Van Wesep R, Resau JH, Sun CC. The effect of immersion formaldehyde fixation on human placental weight. Arch Pathol Lab Med. 1991 Jul;115(7):726-8.
4. Novak RF. A brief review of the anatomy, histology, and ultrastructure of the full-term placenta. Arch Pathol Lab Med. 1991 Jul;115(7):654-9.
5. Langston C, Kaplan C, Macpherson T, Manci E. Practice guideline for examination of the placenta. Arch Pathol Lab Med. 1997 May;121(5):449.