A COMPERATIVE STUDY ON RATIO OF CALCIUM AND PHOSPHORUS IN SERUM AND URINE AMONG PRE AND POSTMENOPAUSAL WOMEN.

Abstract

Osteoporosis is a bone disease resulting in reduction in bone mass and the bone become susceptible for fracture. The major factor involved in the development of osteoporosis includes, low calcium intake or decrease in Calcium absorption rate in aged population, bone strength in later life depends on development of bones earlier in life, adequate calcium intake during youth is essential to achieve peak bone mass. The Serum Calcium and Phosphorus, Urinary Calcium and Phosphorus were estimated by spectrophotometrically by O-cresolphthalein and Phosphomolybdate method respectively. Urinary creatinine was estimated by Spectrophotometric Jaffe’s reaction. In our study, Urinary Calcium excretion was significantly increased with that of premenopausal woman of Indian sub population. Present study is an attempt to underscore urinary calcium quantification does increase diagnostic sensitivity by measuring it as derive parameter – CCR. It could as well be considered as an indicator for therapeutic intervention by studying large pre and postmenopausal woman population.