Affiliation:
1. Assistant Professor, Department of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur.
2. Senior Resident, Department of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur.
3. Assistant Professor, Department of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur
Abstract
Thrombotic thrombocytopenic purpura (TTP) is a syndrome characterized by microangiopathic hemolytic
anemia, thrombocytopenia, neurological abnormalities, fever and renal dysfunction. Early clinical
suspicion and presumptive diagnosis of TTP helps in timely initiation of treatment modalities specic for TTP which may prove to
be lifesaving and thus augment in reducing the mortality rate of TTP which is estimated to be 80 – 90 % if left untreated. We report
a case of a known case of multiple myeloma who developed TTP which proved fatal despite plasmapheresis. Signicant autopsy
ndings of presence of microthrombi in the microvasculature of multiple organs is also highlighted.
Subject
General Environmental Science,Renewable Energy, Sustainability and the Environment,Paleontology,Stratigraphy,Global and Planetary Change,Paleontology,Stratigraphy,Global and Planetary Change,Atmospheric Science,Environmental Science (miscellaneous),Global and Planetary Change,Management, Monitoring, Policy and Law,Atmospheric Science,General Environmental Science,Environmental Chemistry,Management, Monitoring, Policy and Law,Atmospheric Science,Geography, Planning and Development,Global and Planetary Change,Atmospheric Science,Global and Planetary Change,Atmospheric Science,Global and Planetary Change,Pharmacology,Toxicology,Pharmacology (medical),Cardiology and Cardiovascular Medicine