STUDY OF ELECTROLYTE IMBALANCE IN ACUTE CORONARY SYNDROME PATIENTS; A HOSPITAL BASED STUDY.-Reference-Cited by-同舟云学术

STUDY OF ELECTROLYTE IMBALANCE IN ACUTE CORONARY SYNDROME PATIENTS; A HOSPITAL BASED STUDY.

Published:2020-08-01 Issue: Volume: Page:1-3
ISSN:
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
language:en
Short-container-title:ijsr

Author:

Ranjan Rajiv¹,Singh Sangeeta B.²,Mahajan Shikhaa³,Kumari Asha⁴,Singh Nikita⁵,Chawla Harsh Vardhan⁵,Sharma Vivek⁶

Affiliation:

1. PG Resident (MD Biochemistry 3rd Year), Department of Biochemistry, SHKM Government Medical College, Nalhar, Nuh, Haryana, India.

2. Professor and HOD, Department of Biochemistry, SHKM Government Medical College Nalhar, Nuh, Haryana, India.

3. Associate Professor, Department of Biochemistry, SHKM Government Medical College Nalhar, Nuh, Haryana, India.

4. Assistant Professor, Department of Biochemistry, SHKM Government Medical College, Nalhar, Nuh, Haryana, India.

5. Ex. Junior Resident, Department of Biochemistry, SHKM Government Medical College Nalhar, Nuh, Haryana, India.

6. Biochemist, Department of Biochemistry, SHKM Government Medical College Nalhar, Nuh, Haryana, India.

Abstract

Introduction: Electrolytes are very essential for normal functioning of vital organs including heart. Electrical activity of the heart is regulated by Na, K and Ca. Normal homeostasis of these electrolytes are vital for normal functioning of heart. Electrolyte imbalance is often common after episode of acute coronary syndrome (ACS) and electrolyte imbalance may have important role in altering the prognosis of ACS. Aims & Objectives: To assess the serum electrolytes imbalance (Na, K and Ca) in ACS patients within first 48 hours of onset of symptoms. Materials and Methods: This hospital based cross sectional study conducted on 50 cases of ACS and 50 healthy controls. Serum Na, K and Ca (total) concentration were estimated in healthy controls and newly diagnosed cases of ACS within 48 hours of onset of symptoms. Result: Mean value of serum Na, K and Ca (total) in case and control group were 138±4.23 and 140±1.99 mEq/L (p=0.0018), 3.87±0.43 and 4.16±0.35 mEq/L (p=0.0006), 8.85±0.59 and 9.68±0.44 mg/dL (p<0.0001) respectively. Hyponatremia, hypokalaemia and hypocalcemia were found in 14% (n=7), 12% (n=6) and 18% (n=9) of ACS patients respectively. Conclusion: There were statistically significant lower levels of serum Na, K and Ca (total) found in ACS patients compared to healthy controls.

Publisher

World Wide Journals

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