Affiliation:
1. Professor & Head Of Department
2. Associate Professor
Abstract
Background: Acute viral hepatitis is a major public health problem worldwide. Hepatitis-A virus (HAV) and Hepatitis E virus (HEV) are two
major hepatotropic viruses responsible for enterically transmitted acute viral hepatitis. To know seroprevalence , clinico- Objectives:
epidemiological factors and co-infection of hepatitis A & hepatitis E virus infection. The study was carried out in the Virology Research Methods:
& Diagnostic Laboratory (VRDL) under Department of Microbiology IGGMC, Nagpur from January to October 2019. Cases included were
children & young adults of both sexes having clinical hepatitis attending OPD and IPD. Blood sample was collected aseptically from each
suspected patient. Serum was separated and tested for presence of IgM antibody against HAV and HEV by using Enzyme Linked Immunosorbant
assay. Out of 184 samples, HAV seropositivity was seen in 13.04 %, HEV seropos Results: itivity in 35.32 %. Maximum cases were seen in age
group of 0-10 years for HAV and 21-30 years for HEV. Male to female ratio was almost equal for both HAV and HEV. Urban population was most
affected Source of water in maximum cases was tap water in urban and well water in rural area. Prevalence of HEV infection among Conclusion:
the acute viral hepatitis cases is much more common than HAV. HEV being caused by feco-oral route, it is very important to have supply of safe
drinking water. Awareness regarding sanitation, hand and food hygiene is the key factor to prevent hepatitis A & E infection.
Subject
Physiology (medical),Ecology, Evolution, Behavior and Systematics,Physiology,General Biochemistry, Genetics and Molecular Biology,General Earth and Planetary Sciences,Pollution,General Environmental Science,Waste Management and Disposal,Artificial Intelligence,Cognitive Neuroscience,Experimental and Cognitive Psychology,Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology,Cell Biology,Molecular Biology,Pharmacology (medical),Gastroenterology,Oncology,Rheumatology,Immunology and Allergy,General Biochemistry, Genetics and Molecular Biology,General Agricultural and Biological Sciences,General Earth and Planetary Sciences,General Environmental Science
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