Affiliation:
1. M.D Department of Obstetrics and Gynecology, Faculty of Medicine, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima 30000, Thailand.
Abstract
The objective is aimed to Assessing risk factors for unsuccessful rate of uterus contraction inhibition in pregnant women 240/7-336/7 weeks of gestation in Maharat Nakhon Ratchasima Hospital The retrospective cohort study approved by the Research Ethics committee of, Maharat Hospital, Nokhon Ratchasima Province Thailand studying pregnant women who were diagnosed with preterm labor pain with gestrational age of 240/7-336/7 weeks at the delivery ward of Maharat Nakhon Ratchasima Hospital and received Dexamethasone(corticosteroid) for the first time in every case between 1 January 2016 – 31 December 2018. From 361 pregnant women with preterm labor pain, 169 women were successful inhibition which was 54.29%. The group with failure inhibition were 165 women which was 45.71%. The factors relating to unsuccessful inhibition of uterus contraction were ANC less than 5 times, Adjusted odd ratios(AORs) 1.74; 95%CI 1.01-3.03, multiple pregnancy AORs 4.42 ; 95%CI 1.96-9.97 Cervical dilatation ≥3 cm AORs 5.93; 95%CI 3.44-10.22, the Effacement ≥ 80%, AORs 3.39; 95%CI 2.07-5.55, transfer from another hospital AORs 13.96; 95%CI 5.24-37.19. The research concludes that the factors relating to unsuccessful inhibition of uterus contraction were ANC less than 5 times, multiple pregnancy, Cervical dilatation ≥3 centimeters, Effacement ≥ 80%,and pregnant women referred from Secondary care center
Reference11 articles.
1. 1. F.Gary Cunningham et al.(2018). William Obstetrics, Preterm birth. (25th ed). United States of America: McGraw-Hill
2. 2. Antenatal corticosteroids revisited: repeat courses. (2000). NIH Consens Statement, 17(2), 1-18. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/11725806
3. 3. National Institutes of Health Consensus Development, P. (2001). Antenatal corticosteroids revisited: repeat courses - National Institutes of Health Consensus Development Conference Statement, August 17-18, 2000. Obstet Gynecol, 98(1), 144-150. doi:10.1016/s0029-7844(01)01410-7
4. 4. American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins.(2016). Practice Bulletin No. 171: Management of Preterm Labor. Retrieved from https://pubmed.ncbi.nlm.nih.gov/27661654/
5. 5. Theplib, A., & Phupong, V. (2016). Success rate of terbutaline in inhibiting preterm labor for 48 h. J Matern Fetal Neonatal Med, 29(5), 841-844. doi:10.3109/14767058.2015.1021671