Clinical Efficacy Of Hyperbaric Bupivacaine With Clonidine In Two Different Doses With Respect To Sensory Characteristics, Motor Characteristics And Recovery Characteristics In Patients Undergoing Lower Limb Orthopaedic Surgeries

Abstract

Background: Intrathecal opiods as adjuvant to local anaesthetics, when administered intrathecally, act synergistically to overcome the property of reduced duration of postoperative analgesia.. Clonidine a selective partial α2 adrenergic agonist administered intrathecally with bupivacaine improved the quality and duration of postoperative analgesia. Methods: In this Randomised comparative study, 60 patients aged between 20 years and 60 years belonging to ASA I and II undergoing lower limb Orthopaedic surgeries were selected. Sample size was calculated by keeping the confidence interval at 95% and power of study at 80%. Results: The mean time of onset of sensory, motor blockade and the time to achieve maximum sensory level and sedation scores was compared in both the groups. The mean duration of effective analgesia in Group BC30 and in Group BC60 was 357.33±6.915 and 425.33±27.131 minutes respectively. Conclusion: In conclusion , the addition of clonidine 60 µg to hypaerbaric bupivacaine intrathecally prolonged both sensory and motor blocked with higher duration of sensory block when compared to motor block of spinal anaesthesia and hence the duration of analgesia when comared to clonidine 30µg .