A CRITICAL EVALUATION OF CLINICOPATHOLOGICAL STUDY ON LIVER FUNCTIONS IN POSTCHOLECYSTECTOMY CASES COMPARED TO PREOPERATIVE STATUS

Abstract

INTRODUCTION: Gallstones [cholelithiasis] are the most common biliary pathology. It is estimated that gallstones affect 10-15% of the population in Western societies. They are asymptomatic in majority of cases (780). In the UK, the prevalence of gallstones at the time of death is estimated to be 17% and may be increasing. Approximately 1-2% of asymptomatic patients will develop symptoms requiring surgery per year, making cholecystectomy one of the most common operations performed by general surgeon. Gallstones are quite common in the general populations and women are affected more often in the ratio of 4:1. AIMS AND OBJECTIVES: Assessment of hepatic status in pre- operative patients in comparison with postoperative patients. Comparative evaluations of derangement of hepatic parameters in the preoperative period of patient undergoing different forms of gallbladder operations (conventional or laparoscopic cholecystectomy). To evaluate the usual time required for return of deranged hepatic function, if any, to normal levels. To analyse the outcome of cholecystectomies in patients with symptomatic cholelithiasis for improvement in the preoperative symptoms. MATERIALS AND METHODS: The study was conducted in a series of 60 cases of chronic calculus cholecystitis.Patients were selected from surgical outpatient Department of Darbhanga Medical College and Hospital. Laheriasarai. The tenure of study was from April 2019 to December 2020. Adetailed clinical history was taken from every patient to ascertain the diagnosis of chronic calculus cholecystitis. RESULTS AND ANALYSIS: The lump was localised in the right hypochondrium extending to the epigastrium or right lumbar region in some cases. The lump was tender and moves with respiration. Dowdy in 1969 described lump abdomen in 11.7% cases. The present ndings corroborated with that of the other research groups. CONCLUSION: Cholecystectomy appears to relieve most of the symptoms of gall stone disease. Biliary pain, nausea, vomiting and fatty food intolerance had better outcome compared to dyspepsia, atulence and heart burn. Some patients tend to develop de novo symptoms in the postoperative period. Despite the persistence or appearance of new symptoms, most of the patients feel satised with the outcome of surgery.