COMPARISON BETWEEN SAFETY AND EFFICACY OF TRANSDERMAL BUPRENORPHINE AND FENTANYL PATCHES FOR THE MANAGEMENT OF POST-OPERATIVE PAIN FOLLOWING LUMBAR SPINAL INSTRUMENTATION.

Author:

Jaluka Dinesh1,Datta Parthasarathi2

Affiliation:

1. Associate Professor. Neurosurgery, R.G.Kar.Medical College & Hospital. Kolkata.

2. Associate Professor. Neurosurgery,N.R.S.Medical College & Hospital. Kolkata.

Abstract

Introduction: Pain is a complex sensory perception. Post-operative pain management is multimodal. We compared transdermal fentanyl and buprenorphine patches for management of post-operative pain following lumbar spinal instrumentation. Material & Methods: A sample size of 60 patients were included equally divided into 2 groups. Group B: Receiving transdermal buprenorphine at 10mcg/hr and Group F: Receiving transdermal fentanyl at 25mcg/hr. Transdermal patches were applied 6 hours before proposed surgery. Statistical analysis was done by SPSS version 25.0, In,Chicago II ,USA and Graph pad Prism version 5. Results & Analysis: Analysis of different data vs group was not statistically significant. Conclusion: Buprenorphine transdermal patch (TDP) is better as it has less adverse events than fentanyl TDP which is a better analgesic

Publisher

World Wide Journals

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Plant Science,Physiology,Biochemistry,Insect Science,Plant Science,Infectious Diseases,Cell Biology,Microbiology (medical),Ecology, Evolution, Behavior and Systematics,Parasitology,Plant Science,Agronomy and Crop Science,Plant Science,Plant Science,Ecology, Evolution, Behavior and Systematics,Complementary and alternative medicine,Pharmacology,Pharmacology,Dermatology

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