Affiliation:
1. Postgraduate, Department of General Medicine, NRIIMS, Visakhapatnam
2. MD, Associate Professor, Department of General Medicine, NRIIMS, Visakhapatnam
Abstract
Indoxacarb is a non-organophosphorous compound. It is a newer insecticide used rarely compared to the more common
organophosphates by farmers. Hence less information is available on its toxic effects in humans. Timely diagnosis and
management in ER can avoid unnecessary mechanical ventilation and other complications. There are few case reports in the literature about
indoxacarb poisoning, most of them requiring mechanical ventilation. This is a case of indoxacarb poisoning resulting in methemoglobinemia and
seizures timely managed with methylene blue and oxygen support without any need for mechanical ventilatory support.
Subject
Safety, Risk, Reliability and Quality,Nuclear Energy and Engineering,General Engineering,General Engineering,Nuclear and High Energy Physics,Nuclear and High Energy Physics,General Energy,Mechanical Engineering,Waste Management and Disposal,Safety, Risk, Reliability and Quality,General Materials Science,Nuclear Energy and Engineering,Nuclear and High Energy Physics,General Engineering,Nuclear Energy and Engineering,Condensed Matter Physics,Nuclear and High Energy Physics
Reference6 articles.
1. Shashibhushan J, Huggi V, Kumar NS, Poojari M, Bobba R. Indoxacarb Poisoning Presenting as Methemoglobinemia and Seizure. J Assoc Physicians India. 2015 Dec;63(12):85–6.
2. Chhabra R, Singh I, Tandon M, Babu R. Indoxacarb poisoning: A rare presentation as methemoglobinaemia. Indian J Anaesth. 2010;54(3):239–41.
3. Park JS, Kim H, Lee SW, Min JH. Successful treatment of methemoglobinemia and acute renal failure after indoxacarb poisoning. Clin Toxicol (Phila). 2011 Oct;49(8):744–6.
4. Wang Q, Rui C, Wang Q, Wang L, Li F, Nahiyoon SA, et al. Mechanisms of Increased Indoxacarb Toxicity in Methoxyfenozide-Resistant Cotton Bollworm Helicoverpa armigera (Lepidoptera: Noctuidae). Toxics. 2020 Sep 17;8(3):71.
5. Yen CK, Ku IT, Chao CM, Lai CC. Methemoglobinemia Caused by Indoxacarb Poisoning. Am J Med Sci. 2017 Jun;353(6):603–4.