ASSESSMENT OF ERYTHROPOIETIN STATUS IN EARLY DIABETIC NEPHROPATHY AND ITS CORRELATION WITH MICROALBUMINURIA

Abstract

Objectives: To investigate serum Erythropoietin levels in patients with early diabetic nephropathy (<5 years) and analyze the relationship between Erythropoietin and Microalbuminuria. Methods: Case population comprised of Type 2 diabetic patients in the age group 18-60 years with diabetes persisting for less than 5 years. Diagnostic criteria for case subject with diabetics was done as per ADA 2016 guidelines. A control group of healthy subjects was used for comparison. Results: Our study shows that Erythropoietin level is signicantly decreased in cases in comparison to controls (p value <0.05). A negative correlation exists between Erythropoietin level and ACR value in cases and also a negative correlation exist between ACR and hemoglobin level in cases. Conclusion: Early Diabetic nephropathy is associated with decreased Erythropoietin level in spite of normal iron storage that warrant frequent monitoring among patients with diabetic kidney disease.