Affiliation:
1. Professor, Department of Neurosurgery, C N Center, GMCH Guwahati
2. Senior Resident, Department of Neurosurgery, C N Center, GMCH Guwahati
Abstract
Primary Pigmented lesions of the Central nervous System are rare and diverse group of entities that run the gamut from Benign to malignant[1].
Among Pigmented CNS Tumor, Primary intracranial melanomas possesses a great interest among Neurosurgeons with its varied Clinical and
Radiological patterns as they are most often confused and misdiagnosed with Meningioma, Schwannoma and thrombosed aneurysms . Primary
cerebral melanomas, derived from the melanocytic cells that are precursor Cells of Melanoblasts considered to be originated from neural crest cells
that are normally present in the leptomeninges. They are rare and occur in around 1% of all melanoma cases[2,4]. Primary intracranial malignant
melanoma accounts 0.1% of intracranial neoplasms[3]. This report highlights a case of Primary Intracranial malignant melanoma of clivus in 40
year male, who has undergone left Pterional Craniotomy Trans Sylvian approach and excision of Tumor after proper dermatological,
ophthalmological and systemic evaluations to exclude presence of any other lesions in the body. Which was proved malignant melanoma via
Histopathology. Herein we have reported this case for its rarity and consideration as differential for prompt treatment.
Subject
Agronomy and Crop Science,Applied Microbiology and Biotechnology,Bioengineering,Food Science,Biotechnology,Biochemistry,Catalysis,Biotechnology,Cell Biology,Molecular Biology,Biochemistry,Biophysics,Biochemistry,Biochemistry,Biomedical Engineering,Environmental Engineering,Bioengineering,Biotechnology,Genetics,Molecular Biology,General Medicine,Ecology, Evolution, Behavior and Systematics,Biochemistry,Cell Biology,Molecular Biology,Biochemistry,Biochemistry,Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology