“A COMPARATIVE STUDY OF NERVE CONDUCTION VELOCITIES IN INDIVIDUALS WITH NORMALAND IMPAIRED GLUCOSE TOLERANCE”

Abstract

INTRODUCTION: Diabetes mellitus is a global problem. The prevalence of diabetes mellitus is growing rapidly worldwide and is reaching epidemic proportions. Diabetic neuropathy is the most common and troublesome complication of diabetes mellitus, accounting for 28%, leading to great morbidity and resulting in a huge economic burden for diabetes care. AIMS AND OBJECTIVES: AIM To look for changes in Nerve Conduction Velocity in early stages of Glucose Intolerance i.e. in Impaired Glucose Tolerance (IGT). OBJECTIVES: To determine the Nerve Conduction Velocity of Peripheral Nerve in lower limb in Normal Glucose Tolerance (NGT) subjects, IGT patients. To compare and analyze Motor NCV of Peroneal Nerve and Sensory NCV of Sural Nerve in Normal Glucose Tolerance subjects, IGTpatients. MATERIALS AND METHODS: 50 subjects with normal glucose tolerance and 50 subjects with impaired glucose tolerance were selected and the study was conducted in Government General Hospital, Guntur. RESULTS AND OBSERVATIONS:there are signicant changes in latency, amplitude and velocity in the 2 groups. CONCLUSION: The early detection of abnormal glucose metabolism is particularly important, as treatments will probably be most effective if administered early in the course of neuropathy,