“TOOTH AGENESIS: A REVIEW OF MOLECULAR BASES”

Author:

F. Luciani1,E. Papa1,R. Costantini1,R. Condò1,Calabrese L.2

Affiliation:

1. ‘‘Tor Vergata” University of Rome School of Medicine and Surgery “Oral Surgery” Specialization

2. Director and chief, ‘‘Tor Vergata” University of Rome School of Medicine and Surgery “Oral Surgery” Specialization

Abstract

Both recent progresses reached in molecular genetics and “Genoma Umano” project have collected positive results for the identication of those different genes involved in pathogenesis of human race pathologies. Just like any other medicine branch, dentistry could prot from molecular biology recent progresses, showing several answers to unknown questions. This knowledge also concerns genesis of pathologies interesting tissues (enamel, dentin, pulp, cementum), teeth formation and development. Our work aims at verifying, by means of a literature review, the current knowledge and the state of art of dental agenesis molecular bases, in order to better understand the etiopathogenetic role of inheritance and transmission of hypodontia. Our literature review elaborates on dental agenesis biomolecular bases, in order to group in one review all the new ndings in genetic eld about dental anomalies, attempting to give the clinician more information to make easier to manage one of the most discussed surgical dental pathology.

Publisher

World Wide Journals

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