SUCCESSFUL MANAGEMENT OF SPHENOID RELAPSE OF MULTIPLE MYELOMA WITH RADIATION THERAPY: A CASE REPORT-Reference-Cited by-同舟云学术

SUCCESSFUL MANAGEMENT OF SPHENOID RELAPSE OF MULTIPLE MYELOMA WITH RADIATION THERAPY: A CASE REPORT

Published:2021-11-01 Issue: Volume: Page:1-2
ISSN:
Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
language:en
Short-container-title:IJAR

Author:

Bazine A.¹,Torreis M.²,Elmarjany M.³,Benlemlih M.⁴,Maghous A.⁴,Marnouche A.⁴,Houmadi M.³,Andaloussi KH.³,Haddadi KH.⁴,Sifat H.⁴

Affiliation:

1. Radiotherapy department of Military Instruction Hospital Mohamed V, Rabat, Morocco. Faculty of Medicine and Pharmacy, Fez, Morocco. Sidi Mohamed Ben Abdellah University, Fez, Morocco. Mohamed V University, Rabat, Morocco.

2. Faculty of Medicine and Pharmacy, Fez, Morocco. Sidi Mohamed Ben Abdellah University, Fez, Morocco.

3. Radiotherapy department of Military Instruction Hospital Mohamed V, Rabat, Morocco

4. Radiotherapy department of Military Instruction Hospital Mohamed V, Rabat, Morocco.

Abstract

Multiple myeloma (MM) is typically characterized by neoplastic proliferation of plasma cells in the bone marrow and can result in extensive skeletal destruction. Involvement of skull base is extremely rare, especially sphenoid bone. We report in this work the case of a 62-year-old woman, who presented with a sphenoid relapse of multiple myeloma treated with radiation therapy, with signicant clinical improvement and almost complete disappearance of the sphenoid metastasis. We shed light, through this case, on the rarity of sphenoid metastases in multiple myeloma and on the role of radiotherapy in the management of this type of location.

Publisher

World Wide Journals

Reference9 articles.

1. Kyle RA, Gertz MA, Witzig TE, et al. Review of 1027 patients with newly diagnosed multiple myeloma. Mayo Clin Proc 2003;78:21.

2. Mandal S, Chaudhuri T, Kar M, Roy R, Roy S (2015) A Case of Multiple Myeloma Presenting with Plasmacytoma of Body of Sphenoid Bone: A Case Report J Clin Exp Oncol 4:3.

3. Higurashi M, Yagishita S, Fujitsu K, Kitsuta Y, Takemoto Y, Osano S . Plasma cell myeloma of the skull base: report of two cases. Brain Tumor Pathol 2004;21:135–141.

4. Kumar S, Paiva B, Anderson KC, et al. International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma. Lancet Oncol 2016;17:e328.

5. Bachmeyer C, Levy V, Carteret M, et al. Sphenoid sinus localization of multiple myeloma revealing evolution from benign gammopathy. Head Neck 1997;19:347–50.