ADVERSE DRUG REACTIONS: AN ACTIVE MONITORING STUDY IN A TERTIARY CARE HOSPITAL

Abstract

Identication of Adverse drug reactions is a key factor to improve the overall health outcome. The study aimed to assess the adverse drug reactions reported in hospitalized patients. The study was conducted for 6 months to assess the incidence of adverse drug reactions where the assessment of various parameters was done using Naranjo, modied Schumock and Thornton, and modied Hartwig and Siegel scale. A total of 500 cases were analyzed, out of which 38 adverse drug reactions were reported. The demographic details showed that geriatric male patients have a greater number of adverse drug reactions than females. It was found that rashes were the most commonly seen adverse drug reaction and most of occurred adverse drug reactions were found to be probable. Drugs acting on the central nervous system showed a greater number of adverse drug reactions and the most affected system was found to be the skin. Occurrence of adverse drug reaction was also found and the causality, preventability, severity, seriousness, and outcome were found using various scales. A prospective study was conducted to assess the knowledge among the healthcare providers by circulating questionnaire survey forms to 200 healthcare providers. The practice of adverse drug reaction reporting is poor among healthcare providers due to various reasons like lack of knowledge, unavailability of reporting form, not knowing where and how to report, and lack of time. However, this study reveals that there is a greater need to create awareness and promote reporting of adverse drug reactions for better health outcomes.