Affiliation:
1. Professor; Department Of Medicine, Dr. Pinnamaneni Siddhartha Institute Of Medical Sciences & Research Foundation
2. Senior Resident, Department Of Medicine, Dr. Pinnamaneni Siddhartha Institute Of Medical Sciences & Research Foundation
3. Junior Resident, Department Of Medicine, Dr. Pinnamaneni Siddhartha Institute Of Medical Sciences & Research Foundation
Abstract
Diabetic neuropathy occurs in 50% of individuals with long standing diabetes mellitus. It is the most dreadful microvascular complication of
poorly controlled long standing diabetes mellitus, ending up in amputation in worst cases. It is signicantly associated with age, duration of
diabetes, smoking and HbA1c. Neuropathy can cause sensory decit, neurological disorder, limb ulcers, osteomyelitis and lead to amputation.
Nearly 50% of diabetic peripheral neuropathy is asymptomatic. Methods: 80 cases who were diabetic and without any symptoms of neuropathy
were taken into the study and both motor and sensory nerve conduction studies were performed. Results:In this study, patterns of nerve conduction
velocities show abnormal conduction patterns in 65% of individuals. Of these demyelinating axonal sensorimotor neuropathy is predominant
(20%), followed by demyelinating sensorimotor (15%), axonal sensory (10%), demyelinating sensory (10%), demyelinating motor (5%), axonal
sensorimotor (2.5%) and axonal motor (2.5%). Conclusions: Nerve conduction studies even in asymptomatic cases may prove to be valuable
indices of progression to full blown diabetic neuropathy in due course and help initiate prophylactic measures to retard its progress
Subject
General Physics and Astronomy,General Materials Science,General Chemistry,General Medicine,Complementary and alternative medicine,General Medicine,General Medicine,General Medicine,Applied Psychology,Experimental and Cognitive Psychology,Anesthesiology and Pain Medicine,Space and Planetary Science,Astronomy and Astrophysics,Ecology, Evolution, Behavior and Systematics
Reference11 articles.
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2. Dr Suneetha. G, Dr Satyanarayana Prasad. Evidence of Nerve Conduction Defects in Type-II Diabetic Patients without Neuropathic Symptoms. JMSCR Volume 05 Issue 05 May 2017
3. Swati Mahajan, Jayant Makwana, Prashant Khadayate Comparison of sensory nerve conduction in upper limb and lower limb in asymptomatic diabetics and normal volunteers. Int J Basic Appl Physiol.,5(1),2016
4. Agarwal S, Lukhmana S, Kahlon N, Malik P, Nandini H. Nerve conduction study in neurologically asymptomatic diabetic patients and correlation with glycosylated hemoglobin and duration of diabetes. National Journal of Physiology, Pharmacy and Pharmacology. 2018;8(11):1533-8.
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