Affiliation:
1. Professor, Department of General Surgery, G.S.V.M Medical College ,Kanpur
2. Professor, Department of General Surgery, Kannauj Medical College ,Kanauj
3. Associate Professor , Department of Radio-diagnosis , G.S.V.M Medical College ,Kanpur
4. Associate Professor , Department of Pathology, G.S.V.M Medical College ,Kanpur
5. Post Graduate Trainee, Department of General Surgery, G.S.V.M Medical College ,Kanpur
Abstract
Background: The purpose of this study was to assess the accuracy of preoperative CT imaging for predicting pathologic
nodal ECE (pECE). To estimate the accuracy of the presence of radiologic extranoda AIM: l extension (rENE) in
reference to pathologic extranodal extension (pENE) in patients with oral cavity squamous cell carcinoma (OSCC) MATERIALS AND
METHODS: This is a prospective study in GSVM Medical College, LLR & Associated Hospitals, Kanpur (UP). The records of 50 consecutive
patients with oral cavity cancer (OCC) who underwent preoperative CT imaging before initial surgical resection and neck dissection between
2020 and 2021 were reviewed. Specimens with pECE had the extent of ECE graded on a scale from 1 to 4. Radiographic ECE was RESULTS:
documented in 6 patients (12%), and pECE was observed in 11 (22%). Sensitivity, specicity, positive predictive value (PPV), and negative
predictive value (NPV) were 45.4%, 97.4%, 83.6%, and 86.3%, respectively. The sensitivity of radio- graphic ECE increased from 40% for grade
1 to 2 ECE, to 50% for grade 3, and 50% for grade 4. Radiographic ECE criteria of adjacent structure invasion was a better predictor than irregular
borders/fat stranding for pECE. Radiographic ECE has poor sensitivity, but excellent spec CONCLUSION: icity for pECE in patients who
undergo initial surgical resection. PPV and NPV are reasonable for clinical decision making. The performance of preoperative CT imaging
increased as pECE grade increased.
Subject
Cellular and Molecular Neuroscience,Developmental Neuroscience,Neurology,Toxicology,General Neuroscience,Toxicology,General Neuroscience,Cellular and Molecular Neuroscience,Developmental Neuroscience,Toxicology,Nuclear and High Energy Physics,Atomic and Molecular Physics, and Optics,Anthropology,Visual Arts and Performing Arts,Speech and Hearing,Public Health, Environmental and Occupational Health,Otorhinolaryngology,Mechanical Engineering,Acoustics and Ultrasonics,Mechanics of Materials,Condensed Matter Physics,General Materials Science,General Engineering,Industrial and Manufacturing Engineering,Public Health, Environmental and Occupational Health,Mechanical Engineering,Acoustics and Ultrasonics,Aerospace Engineering,Automotive Engineering,Building and Construction