Affiliation:
1. Junior resident III , Department of physiology, JNMCH ,AMU, Aligarh
2. Professor & Chairman , Department of Physiology, JNMCH, AMU, Aligarh.
3. Assistant Professor, Department of Obstetrics & Gynaecology, JNMCH, AMU, Aligarh.
Abstract
Background: There is an established link between the change in levels of Estrogen and its affect on mental health in middle age females. Objective:
To see the correlation between serum Estrogen levels and cognitive functions in the study groups. Methods: This was a hospital based crosssectional study involving a total of 90 females who were divided into three groups of 30 females each, based on their age and menstrual
history.These groups were premenopausal(31-35 years ) ,early perimenopausal( 36-40 years,),late perimenopausal (41- 45 years).The level of
serum Estrogen was estimated in all the study subjects and their cognitive assessment was done using Montreal Cognitive Assessment
scale(MoCA). One way ANOVA was used to asses the signicance. Results: There is a correlation between cognitive decline and serum estrogen
levels in late perimenopausal age group as compared to early perimenopausal and premenopausal age group. Conclusion: There is a signicant
relationship between estrogen levels and cognitive functions in middle aged females.
Subject
Agronomy and Crop Science,Applied Microbiology and Biotechnology,Bioengineering,Food Science,Biotechnology,Biochemistry,Catalysis,Biotechnology,Cell Biology,Molecular Biology,Biochemistry,Biophysics,Biochemistry,Biochemistry,Biomedical Engineering,Environmental Engineering,Bioengineering,Biotechnology,Genetics,Molecular Biology,General Medicine,Ecology, Evolution, Behavior and Systematics,Biochemistry,Cell Biology,Molecular Biology,Biochemistry,Biochemistry,Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology