A COMPARATIVE STUDY OF LIPID PROFILE AND ECG CHANGES IN ISCHEMIC AND HAEMORRHAGIC STROKE

Abstract

Objective The study was done to compare the risk factors, lipid prole, and ECG changes in patients of ischemic and haemorrhagic stroke. Methodology All patients clinically and radiologically diagnosed to be ischemic or haemorrhagic stroke, detailed history, clinical examination, ECG, CT scan brain and routine blood investigation was done on arrival.MRI brain was done when required. Repeat CT scan brain and clinical evaluationwas done after 24 hours to look for complications or improvements, as well as ECG was repeated to look for development of any further changes and comparison was made. Results Out of 80 patients, 34(42.5%) suffered from Haemorrhagic stroke and 46(57.5%) suffered from ischemic stroke. Out of 34 patients who suffered from haemorrhagic stroke 25 had history of hypertension, 22 had history of diabetes, 20 had history of smoking, 12 had history of stroke, 22 had history of alcohol intake, 8 was found to have obesity, and 12 had sedentary lifestyle. Out of 46 ischemic stroke patients, 44 had history of hypertension, 34 had history of diabetes, 24 had history of smoking, 18 had history of stroke, 22 had history of alcohol intake, 9 were obese, and 23 had sedentary lifestyle. Lipid prole was found to be elevated in both type of stroke, however, total cholesterol and LDL were more in ischemic comparatively, while HDL and triglyceride was higher in haemorrhagic. ECG changes were seen in 52.5% of the patients and were more common in haemorrhagic stroke. Conclusion It was seen that the risk factors such as older age, hypertension, diabetes, dyslipidemia, sedentary lifestyles favoured ischemic stroke and smoking, alcohol, obesity favoured haemorrhagic stroke. Higher cholesterol and LDLlevels favoured ischemic more than haemorrhagic stroke. ECG changes were more common in haemorrhagic stroke