STUDY TO EVALUATE CLINICOPATHOLOGICALASSOCIATION BETWEEN DEPTH OF INVASION AND NECK NODE METASTASIS IN ORAL CAVITY CARCINOMA

Author:

Agrawal Yash1,Nirwan Siddharth2,Singh Jat Kailash2,Singhal Pawan3,Sharma Man Prakash3,Rohila Vikas2

Affiliation:

1. Junior Resident, Department of ENT, Sawai Man Singh Medical College, Jaipur

2. Assistant Professor, Department of ENT, Sawai Man Singh Medical College, Jaipur

3. Senior Professor, Department of ENT, Sawai Man Singh Medical College, Jaipur

Abstract

Objective: To evaluate association between depth of invasion and neck node metastasis. Methods:Aprospective observational study was carried at Department of ENT, Sawai Man Singh Medical College over a period of one year in which 102 patients of oral carcinoma were included that underwent wide local excision with neck dissection. Results:The mean depth of invasion was 10.59 with 7.44 standard deviation (range 2-45 mm). Lymph node metastasis was present in 3 out of 27 patients with a DOI < 5mm (11%), in 13 out of 39 with a DOI 5.1-10 mm (34%) and in 8 out of 36 with DOI >10mm (22%). Chi square value was 30.79 and the p-value was<0.001. Conclusion: The risk of lymph node metastasis increased with increased depth of invasion.

Publisher

World Wide Journals

Subject

Mechanical Engineering,Mechanics of Materials,Biomedical Engineering,Medicine (miscellaneous),Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine,General Immunology and Microbiology,Endocrine and Autonomic Systems,Endocrinology, Diabetes and Metabolism,Pharmacology (medical),Psychiatry and Mental health,Pharmacology,General Nursing,Food Science,Endocrinology, Diabetes and Metabolism,Internal Medicine

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