Affiliation:
1. MD, Assistant Professor, Department of the General Medicine, Thanjavur Medical College & Hospital, Thanjavur.
2. MD, Junior Resident, Department of General Medicine, Thiruvarur Medical College & Hospital, Thiruvarur.
3. III Year Post Graduate, Department of General Medicine, Thanjavur Medical college, Thanjavur.
Abstract
Background: Dengue is an arthropod borne viral infection caused by avivirus which causes simple fever to severe complications like Dengue
Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Hemophagocytic syndrome (HS) is being frequently reported in patients with
severe dengue. Hyperferritinemia (levels above 10000ug/L) is a agship sign of HS. Fi Methods: fty patients of Dengue IgM Positive cases of age
more than 18 admitted in Thanjavur medical college formed the study group. These patients were analysed clinical symptoms,Laboratory
investigation- Platelet count and Serum Ferritin level - Its Correlation with Severity of Dengue fever was analysed. Duration of hospital Results:
stay showed mild positive correlation with age, moderate positive correlation with serum ferritin and moderate negative correlation with platelet
count. There was moderate negative correlation between serum ferritin and platelet count. As the serum ferritin level increased there was a decrease
in platelet count
Subject
Mechanical Engineering,Mechanics of Materials,Biomedical Engineering,Medicine (miscellaneous),Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine,General Immunology and Microbiology,Endocrine and Autonomic Systems,Endocrinology, Diabetes and Metabolism,Pharmacology (medical),Psychiatry and Mental health,Pharmacology,General Nursing,Food Science,Endocrinology, Diabetes and Metabolism,Internal Medicine
Reference15 articles.
1. Harrison's Principles of Internal Medicine, 20e Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Jameson J, & Fauci A.S., & Kasper D.L., & Hauser S.L., & Longo D.L., & Loscalzo J(Eds.),Eds.
2. GuzmanMG, HalsteadSB, ArtsobH, BuchyP, FarrarJ,etal.(2010) Dengue: a continuing global threat. Nat Rev Microbiology 8: S7– S16.
3. Bhatt S, Gething PW, Brady OJ. The global distribution and burden of dengue.Nature. 2013;496(7446):504-7.
4. Guglani L, Kabra SK. T cell immunopathogenesis of dengue virus infection. Dengue Bull, 2005; 29: 58–68.
5. Environmental Health Project, Dengue Fever: An Environmental Plague for the New Millennium?1999; Camp Dresser & McKee International Inc, Cambridge, Massachusetts. 1–8.