Affiliation:
1. Associate Professor, Dept. of Biochemistry, Tezpur Medical College and Hospital, Assam.
2. Senior Resident, Dept. of Biochemistry, Tezpur Medical College and Hospital, Assam.
3. Senior Resident, Dept. of Biochemistry, Tripura Medical College and Hospital, Assam.
4. Professor and Head, Dept. of Biochemistry, Tezpur Medical College and Hospital, Assam.
Abstract
Aim: Prevalence of metabolic syndrome in patients with type 2 diabetes mellitus in North East India
Introduction: Metabolic syndrome is an increasingly prevalent condition which predisposes the
individual to diabetes mellitus (DM) and atherosclerotic cardiovascular disease (ASCVD). The diagnosis of metabolic
syndrome is made as per the AHA/NHLBI 2005 criteria. As per this criteria, metabolic syndrome can be diagnosed by the
presence of any 3 of the ve factors (elevated waist circumference, elevated triglycerides, reduced HDL-C, elevated blood
pressure and elevated fasting glucose). This study is being conducted to study the prevalence of metabolic syndrome among
patients with type 2 diabetes mellitus. Materials and Methods: In this prospective cross-sectional study, 100 adult patients of
type 2 diabetes mellitus were selected. Physical examination was conducted including BMI, waist circumference and blood
pressure. Blood samples were collected after 14 hours fasting for estimation of serum fasting glucose, serum HDL-C, serum
LDL-C, serum triglyceride (TG) and serum cholesterol. The prevalence of metabolic syndrome among the study subjects was
accordingly calculated. Results: Among the participants, 57 % were males and 43 % were females. The median age was 57
years (range from 34-78 years). 67% of patients with type 2 diabetes mellitus in this study had metabolic syndrome while 33%
did not have metabolic syndrome. The prevalence of metabolic syndrome among males and females was 61% and 74%
respectively. Conclusion: This study showed that the prevalence of metabolic syndrome is quite high among patients with
diabetes mellitus. Increased waist circumference was the most common abnormal parameter among others for the diagnosis
of metabolic syndrome. Application of lower cut-off values for waist circumference among Asians may help in increasing the
diagnostic yield.
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