EFFECT OF ALTITUDE ON FEV AND FVC SPIROMETRIC PARAMETERS 1 IN THE SECOND TRIMESTER ANTENATAL MOTHERS

Author:

S Thenmozhi1,R Shanmughavadivu.2,N Neelambikai.3

Affiliation:

1. Assistant Professor, Institute of Physiology And Experimental Medicine, Madras Medical College, Chennai 3, Tamil Nadu, India.

2. Professor And Head, Department of Physiology, Coimbatore Medical College, Coimbatore 14, Tamil Nadu, India.

3. Professor, Department of Physiology, Meenakshi Medical College, Kanchipuram, Tamil Nadu, India.

Abstract

BACKGROUND:Pregnancy is associated with various physiological and psychological changes in the antenatal mother. Among these, the changes in the respiratory functions are more signicant. There are various factors which inuence the respiratory function of the antenatal mother such as altitude of the residence, diet and life style Of these, altitude of the residence . plays an important role. To compare the pulmonary function of antenatal mothers living AIM : MATERIALS at high altitude and plains. &METHODS:This cross sectional study involves 60 healthy uncomplicated antenatal mothers in II trimester of pregnancy irrespective of either primi or multigravida within the age group of 18-30 years (30 of them residing at altitude of about 2268 meters from the sea level and 30 of them residing in plains). After measuring the height, weight and body mass index, pulmonary function of these antenatal mothers were assessed by using computerized spirometer in sitting position. Among the various parameters of lung function, forced expiratory volume during rst second (FEV )and forced vital capacity (FVC)values(in liters) were taken. The values are tabulated in a Microsoft 1 STATISTICAL ANALYSIS: excel sheet and statistically analyzed by “Independent t test” and Karl Pearson's coefcient of correlation by using SPSS 23 software. RESULTS: In the present study, when the data are analyzed by “Independent t test” , the p value of demographic variables, FEV1, FVC and FEV1/FVC of antenatal mothers in the second trimester living in high altitude and plains is not less than 0.005(statistically not signicant). By correlating the demographic variables of the antenatal mothers living in high altitude and plains by using Karl Pearson's coefcient of correlation, statistically signicant result between the demographic variables and spirometric parameters of antenatal women residing in high altitude and plains. The present study shows that there is no si CONCLUSION: gnicant different in the pulmonary function test of antenatal mothers in the second trimester of pregnancy residing in high altitudes and plains.

Publisher

World Wide Journals

Reference18 articles.

1. Das TK, Jana H. Maternal airway functions during normal pregnancy. Indian J MedSci 1991;45(10):265-8.

2. Wagner PD, Araoz m, Boushel R, et al. pulmonary gas exchange and acid base state at 5,260 m in high altitude Bolivian and acclimatized lowlanders. J ApplPhysiol 2002;92(4):1393-1400.

3. Cugell DW, Frank NR, Gaensler EA, Badger TL. Pulmonary function in pregnancy.1. Serial observation in normal women. Am Rev Tuber 1953;67:568-597.

4. Lehmann V, Fabel H.( investigation of respiratory function in pregnancy.I. Vital capacity). Z GeburtshilfePerinatol 1973;177(6):387-396.

5. Gazioglu K, Kaltreider NL, Rosen M, Yu PN. Pulmonary function during pregnancy in normal women and in patients with cardiopulmonary diseases. Thorax 1970;25(4);445-450.

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