RECENT ADVANCES IN LABORATORY DIAGNOSIS OF SYSTEMIC AUTOIMMUNE DISEASES.

Abstract

Introduction: Autoimmunity is a condition in which the body's own cells which are immunocompetent and the antibodies, acts against its own self-antigen which will result in structural and functional damage to the body. The diseases caused by this phenomenon are called Autoimmune diseases. Autoimmune diseases are more commonly seen in females. Hundred thousands of individuals in the Western countries are affected. The diagnosis is made from the clinical presentation of the patient with which a differential diagnosis is made, following which various tests both phenotyping methods and genotyping methods are carried out to conclude the nal diagnosis. Conclusion: The genotyping methods play the most important role in the laboratory diagnosis of systemic immune diseases.