AGGRESSIVE ANGIOMYXOMA OF ARM WITH IMMUNOHISTOCHEMISTRY STUDY - A CASE REPORT

Abstract

Aggressive angiomyxoma (AA) is a soft-tissue tumor of mesenchymal origin. It is rare type of tumor occurs commonly in genital, perineal or pelvic region in reproductive age female. It's occurrence in male is very rare and acral site being extremely rare. It exhibits marked tendency for local recurrence and hence the name aggressive. It has risk of distant metastasis though it is extremely low. We report a case of AA in a 34-year-old male presenting with right arm swelling. Fine needle aspiration cytology of the growth was not of much signicance. The tumor was excised and submitted for histopathological examination. A diagnosis of aggressive angiomyxoma was made based on characteristic histological features. Recently, the terminology has been changed to deep angiomyxoma instead of aggressive as the recurrences occur many years after the initial excision. In fact, it has become evident that these neoplasms have a favorable, less aggressive course if initially completely excised with negative margins.Wide local excision with 1-cm margin is considered optimal. Inspite of rarity of angiomyxoma incidence, it is extremely rare in males and site as well.