COMPARATIVE STUDY OF CT-SCAN FINDINGS WITH BIOPSY IN LIVER MASSES DONE AT A TERTIARY CARE CENTER

Abstract

Background: More than 80% of all primary hepatic malignancies are hepatocellular carcinoma. Identification of a liver lesion depends on the attenuation difference between normal liver and the lesion. CT helps in detecting tumors and their size in liver quiet successfully. Accurate detection of liver mass is crucial for the deciding the treatment regimens. Objective: The study was undertaken to compare the results of CT-scan to histopathology findings. Methodology: This cross-sectional study was carried out in the Department of Radiodiagnosis and Imaging, Dr. Vitthalrao Vikhe Patil Foundation’s Medical College, Ahmednagar in association with Department of pathology of the concerned institute for histopathological diagnosis from 01-03-2014 to 28-02-2015 for a period of one year. Patients having hepatic mass of any sex or age presenting in the hospital were included in the study. The exclusion criteria were as patients refusing consent, or CT-scan and/or biopsy, known adverse reaction to contrast agent. CT scan and histopathology were done in all the subjects. Result: 50 subjects were studied in this study. Mean age of all subjects was 52.88 ± 16.03 years with a range of 18 year to 85 years. 40 cases were male in the study group. Maximum number of cases were in the age group 40-59 years. Out of 28 confirmed malignant cases by histopathology, 27 cases were diagnosed as malignant by CT scan too. Sensitivity of CT to diagnose malignant lesion was 96.4%, specificity 86.4%, accuracy 92%, positive predictive value 90% and negative predictive value 95%. Conclusion: CT scan can be used as a tool for the detecting of malignant liver masses.