TOTAL CALCIUM AND ALBUMIN CORRECTED CALCIUM AS PROGNOSTIC SEVERITY MARKERS IN ACUTE PANCREATITIS

Abstract

Aim: to assess the Total Calcium and Albumin-Corrected Calcium as prognostic severity markers and Organ dysfunction. Background: Acute pancreatitis having variable involvement of regional tissues or remote organ systems can lead to high mortality rate in severe form. Early assessment to identify severity becomes essential. Materials & Methodology: A prospective study was conducted in K.R.Hospital, Mysore Medical College & Research Institute, from November 2019 to July 2020. All cases of Acute Pancreatitis during this period were assessed for severity and Total Calcium and Albumin Corrected calcium were assessed in them to assess the severity and their correlation. Results: A total of 96 patients were included in the study and in accordance with the updated Atlanta Classification, 63 patients presented with mild AP, 22 with moderately severe AP, and 11 with severe AP. The maximum TC cut-off point was 7.5 mg/dL, with values of S, 90.9%; Sp, 78.8%; PPV, 35.7%, and NPV, 98.5%. The maximum ACC cut-off point was 7.25 mg/dL, with values of S, 81.8%; Sp, 80%; PPV, 34.6%; NPV, 97.1% respectively . Conclusions: TC and ACC, measured within the first 24 hours, are useful severity predictors in acute pancreatitis, with sensitivity and predictive values comparable or superior to those of the conventional prognostic scales.