MRI CORRELATION WITH CLINICAL STAGING AND HISTOPATHOLOGY FINDINGS IN CERVICAL CANCER

Abstract

AIM AND OBJECTIVES:To correlate MRI findings with clinical findings based on FIGO staging and to evaluate the role of MRI in assessing extension of uterine cervical malignancy in reference to post surgery/staging laparoscopy histopathologic examination where ever available. MATERIAL AND METHODS: This retrospective observational study included 35 patients of histopathologically confirmed carcinoma cervix attending the SRMS Institute of Medical Sciences,Bareilly,UP,who underwent clinical staging and preoperative MRI for evaluation of disease extension between November 2019 to February 2022. RESULTS:the mean age observed was 57.43 ±11.03 years.There is strong percentage agreement between clinical and MRI findings for parametrial invasion, vaginal invasion, hydronephrosis, adjacent pelvic organ involvement and distant metastases with fair to moderate agreement with kappa coefficient except for pelvic side wall involvement in which there was only slight agreement. MRI shows high sensitivity, specificity, PPV and NPV of MRI in diagnosing disease extension in comparison to the histopathology findings. CONCLUSION: Carcinoma cervix is primarily staged clinically as per FIGO guidelines but MRI can modify clinical staging and treatment options. MRI is a reliable diagnostic tool for cervical cancer as it correlates strongly with histopathology