Affiliation:
1. Kajla Singh
2. Department of Ophthalmology, Sree Balaji Medical College and Hospital, Chennai,TN,INDIA
Abstract
Aim: To study the association of components of lipid profile with hypertensive retinopathy in patients of essential
hypertension. Materials and Methods: A Cross Sectional Study was carried out in 80 patients who were diagnosed to
have systemic Hypertension. Patients having myopia, having diabetes, hazy ocular media, and other retinal problems
were excluded from the study.A detailed examination of patient's hypertensive status was done by physician after ruling
out secondary causes of hypertension. Full ophthalmological examination was carried out. All the patients were
investigated for fasting serum lipid profile. Results: Out of the 80 patients with essential hypertension, 55 (55%) had
retinopathy and the remaining 25 (25%) subjects had no retinopathy were mainly concentrated in the 6th decade
(69.70%), increasing thereafter up to 83.78% who were over 60 years of age. This shows the increasing prevalence of
hypertensive retinopathy with increasing age.No sex preponderance toward developing retinopathy was found in this
study . A positive correlation of hypertensive retinopathy was found with total cholesterol (P < 0.002), low-density
lipoprotein (LDL)-cholesterol (P < 0.0001),Serum triglycerides (P < 0.01),and an low-density lipoprotein:high-density
lipoprotein (LDL:HDL) ratio (P < 0.002).Conclusion: The duration of hypertension was found to be strongly associated
with development of hypertensive retinopathy.This study proved a definite association between serum lipid parameters
and prevalence of hypertensive retinopathy.
Subject
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