EVALUATION OF SERUM ALKALINE PHOSPHATASE (ALP) AND CALCIUM LEVEL IN RHEUMATOID ARTHRITIS- A COMPARATIVE STUDY-Reference-Cited by-同舟云学术

EVALUATION OF SERUM ALKALINE PHOSPHATASE (ALP) AND CALCIUM LEVEL IN RHEUMATOID ARTHRITIS- A COMPARATIVE STUDY

Published:2020-10-15 Issue: Volume: Page:56-57
ISSN:
Container-title:PARIPEX INDIAN JOURNAL OF RESEARCH
language:en
Short-container-title:PIJR

Author:

KP Aishwarya¹,GS Reshmy²

Affiliation:

1. Department of Biochemistry, Amrita Institute of Medical sciences and Research Centre, Amrita vishwa vidyapeetham, Kochi, Kerala, India.

2. Department of Biochemistry, Amrita Institute of Medical sciences and Research Centre,Amrita vishwa vidyapeetham,Kochi,Kerala,India.

Abstract

Background: Rheumatoid arthritis is an autoimmune disease that can cause joint pain and damage throughout the body. Rheumatoid arthritis affects about 1% of world population. There will be variation in calcium and alkaline phosphatase levels in rheumatoid arthritis patients. So estimation of these two parameters helps in the diagnosis of the severity of rheumatoid arthritis. Aim & objective: The aim of the study is to find the levels of calcium and alkaline phosphatase in rheumatoid arthritis patients and comparing it with healthy controls to find any deviation from its normal level. Materials & methods: A total of 30 clinically established rheumatoid arthritis patients and 30 healthy age matched control were involved in the study. Serum of the patients and controls were assayed for alkaline phosphatase levels and calcium levels. Result: This study shows an elevated alkaline phosphatase levels and a diminished calcium levels in patients with rheumatoid arthritis when compared to the control. Conclusion: Since the study shows a significant variation in alkaline phosphatase and calcium levels it can serve as a less costly marker for assessing the severity of rheumatoid arthritis.

Publisher

World Wide Journals

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