IN VITRO ANTICANCER ACTIVITY OF CARDIOSPERMUM HALICACABUM (LINN) AGAINST HEPATOCELLULAR CARCINOMA CELL LINE (HEP-G2).

Author:

M. Kulkarni Asawari1,H. Kamble Laxmikant2

Affiliation:

1. School of Life Sciences Swami Ramanand Teerth Marathwada University, Nanded-431606 Maharashtra

2. School of Life Sciences Swami Ramanand Teerth Marathwada University, Nanded-431606 Maharashtra.

Abstract

Cardiospermum halicacabum is important medicinal plant which belongs to Sapindaceae family.In present study, ethanolic leaf extract of Cardiospermum halicacabum was examined for its anticancer activity against Hepatocellular carcinoma cell line (Hep-G2) using MTT assay. The leaf extract shows significant cytotoxic effect with 90% of inhibition when compared to standard drug.

Publisher

World Wide Journals

Reference10 articles.

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2. Arunkumar, S., Valentina, P., Deepa, G., Anitapriyadharshini, K., Rekha, D., Sreekiran, M., & Ramalakshmi, N. (2013). Preliminary phytochemical analysis, HPTLC finger printing and in vitro anticancer screening of extracts of aerial parts of Cardiospermum halicacabum. International Journal of Pharmacy and Pharmaceutical Sciences, 5(3), 301-304.

3. Berridge, M. V., Herst, P. M., & Tan, A. S. (2005). Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnology annual review, 11, 127-152.

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5. Mohaddesi, B., & Dudhrejiya, A. (2018). Evaluation of cytotoxic activity of oil extract and fractions from seeds of Cardiospermum halicacabum L. on various human breast cancer cell lines. Pharmacognosy Magazine, 14(59), 591.

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