Affiliation:
1. Postgraduate, Dept. of General Medicine Saveetha Medical college and Hospital, Chennai
2. Professor, Dept. of General Medicine Saveetha Medical college and Hospital, Chennai
3. Assistant Professor, Dept. of General Medicine Saveetha Medical college and Hospital, Chennai
Abstract
Sickle cell disease (SCD) is an inherited haemoglobinopathy that may present acutely as stroke, vaso-occlusive crisis or
acute chest syndrome. Acute conditions require prompt diagnosis and intensive management to prevent morbidity and
mortality. Here, we present a case of sickle cell anemia treated with therapeutic red cell exchange that manifested as
acute chest syndrome. A 26 year old male who had history of high-grade intermittent fever and cough with expectoration
was diagnosed as pneumonia and put on antibiotics. Peripheral smear showed sickle cells and HPLC showed HbS of
67%. we made a diagnosis of sickle cell anemia with acute chest syndrome. We treated the patient with therapeutic red
cell exchange following which HbS reduced to 24% from the initial 67%. We observed significant clinical improvement
suggesting red cell exchange as a useful therapeutic option for acute sickle cell anaemia.
Subject
Visual Arts and Performing Arts,Communication,Energy Engineering and Power Technology,Renewable Energy, Sustainability and the Environment,Electrical and Electronic Engineering,Computer Science Applications,Mechanical Engineering,Transportation,Cardiology and Cardiovascular Medicine,Molecular Biology,Molecular Biology,Structural Biology,Catalysis,General Engineering,Physical and Theoretical Chemistry,Process Chemistry and Technology,Catalysis,Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis,Cell Biology,Genetics,Molecular Biology,General Medicine