Affiliation:
1. PG-3 Department of Pathology, Gajra raja medical college M.P
2. Assistant Professor Department of Pathology,Gajra raja medical college M.P
3. Professor Department of Pathology,Gajra raja medical college M.P.
4. Professor & Head Department of Pathology,Gajra raja medical college M.P
Abstract
Background: Cervical cancer is unique among human cancers which is mostly attributable to infection. Conventional
PAP smear method is most effective for prevention and detection of cervical cancer but the accuracy of this method is
low.This PAP smear now evolved to Liquid Based Cytology (LBC). Method:All the patients visiting Gynaecology OPD
who fulfilled the inclusion Criteria in the duration starting from 1 January 2020 to 30 June 2021 in the Department of
Pathology of Gajra raja Medical College, Gwalior (MP) were included in this study. 50 atypical smears by Conventional
PAP test were then collected and these cases were subjected to Eziprep Liquid Based Cytology and Conventional PAP
smear in private laboratory setup after taking history and clinical examination. The smears were studied by using 7
morphological parameters. Result: Smears were analysed for adequate cellularity, clean background, uniform
distribution of cells,cellular overlapping,inflammation,distinct cell border,nuclear irregularity and then categorise by
Bethesda reporting system.The results were significant only for clean background,uniform distribution of cells,cellular
overlapping and inflammation. Conclusion: Results of cervical cytology smears by both methods showed that LBC
provides more representative sample with reduced obscuring material,improved clarity allowing better morphological
evaluation.
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