CASE STUDY ON DIABETIC FOOT- MEDICATED COLLAGEN DRESSING VERSUS CONVENTIONAL DRESSING.

Abstract

Aims and Objectives: The aim is to evaluate the clinical efficacy of medicated collagen dressing versus conventional dressing,as topical dressing material in diabetic ulcer to promote healing.In terms of: 1) Healing time 2) Duration of antibiotics 3) Duration of length of stay in hospital. Background: Diabetic foot ulcers are a major source of morbidity, limb loss, and mortality.A prolonged inflammatory response,extracellular matrix degradation irregularities,and increased bacteria presence have all been hypothesized a major contributing factors in the delayed healing of diabetic wounds. Collagen components such as fibroblast and keratinocytes are fundamental to the process of wound healing and skin formation. Wound dressings that contain collagen products create a biological scaffold matrix that supports the regulation of extracellular components and promotes wound healing Methods: The study was conducted in patients admitted with diabetic foot ulcer in the Department of General Surgery,GMERS Hospital,Vadoadara. The no. of patients included in the study was 30, out of which,15 in Group A-Topical dressing with medicated collagen powder (medicated with metronidazole and mupirocin) were applied with operative/bedside surgical debridement whenever indicated and 15 in Group B- Conventional Topical dressing with operative/bedside surgical debridement. Data was analyzed using appropriate software. Results: The results concluded that healing time, duration of antibiotics and duration of stay in hospital were comparatively low in Group A patients then in Group B patients. Conclusion: Medicated Collagen powder dressing is safe and effective in the treatment of diabetic foot ulcer and significantly reduces healing time, duration of antibiotic therapy and duration of stay in hospital.