A CLINICO-EPIDEMIOLOGICAL STUDY ON LEPTOSPIROSIS IN WEST BENGAL: A NEGLECTED CAUSE OF ACUTE FEBRILE ILLNESS
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Published:2022-10-15
Issue:
Volume:
Page:42-45
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ISSN:
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Container-title:PARIPEX INDIAN JOURNAL OF RESEARCH
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language:en
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Short-container-title:PIJR
Author:
Sikdar Rahul1, Gupta Bishal2, Chakraborty Debopriya2, Chakraborti Rinku3, Chowdhury Aparna4, Mondal Saiantani5, Chakraborty Banya6, Bandyopadhyay Bhaswati7
Affiliation:
1. Senior Resident, School of Tropical Medicine, Kolkata 2. Senior Resident, School of Tropical Medicine, Kolkata, 3. Demonstrator, School of Tropical Medicine, Kolkata 4. Molecular Biologist, School of Tropical Medicine, Kolkata 5. Technical officer, School of Tropical Medicine, Kolkata 6. Professor & Head Dept. of Microbiology, School of Tropical Medicine, Kolkata 7. Professor, In-charge Virology unit, Dept. of Microbiology
Abstract
Introduction: Leptospirosis is a major neglected public health problem and is highly underreported in India. It is a
common cause of the acute febrile illness (AFI), but accurate diagnosis is quite challenging and often delayed because
of overlapping symptoms with many other infectious diseases, and limited access to laboratory diagnosis. The aim Aim:
of the study was to assess the proportion of Leptospira infection among patients suffering from AFI in West Bengal and to
analyse socio-demographic characteristics, clinical features, and laboratory parameters of leptospirosis cases.
Materials and methods: Serum samples were collected from 350 hospital-admitted patients suffering from AFI (fever
>five days ≤ two weeks) but without any identifiable cause and tested for Leptospira IgM using PanBio Leptospira IgM
ELISA kit. Clinical features, laboratory parameters and epidemiological data were collected from each patient and
analysed. 91(26%) out of 350 fever cases tested positive for Leptospira IgM ELISA. Most of them were Result: male and
belonged to the age group of 31–60 years (42.85%) and 16–30 years (30.76%). Common symptoms were fever (100%)
myalgia (76.92%), headache (70.32%), icterus (69.23%), vomiting (67.03%) and pain abdomen (65.93%). Conclusion:
Leptospirosis is a common cause of acute undifferentiated febrile illness in West Bengal. Our findings demonstrated the
importance of active surveillance of leptospirosis among cases of acute febrile illness to facilitate its early detection and
prevention of complications.
Publisher
World Wide Journals
Subject
Genetics,Pathology and Forensic Medicine,Law,Pathology and Forensic Medicine,General Medicine,Pathology and Forensic Medicine,Psychiatry and Mental health,Physical and Theoretical Chemistry,Anthropology,Biochemistry, Genetics and Molecular Biology (miscellaneous),Pathology and Forensic Medicine,Analytical Chemistry,Law,Psychiatry and Mental health,Applied Psychology,Electrical and Electronic Engineering,General Computer Science,General Mathematics,Insect Science,Physical and Theoretical Chemistry,Physical and Theoretical Chemistry,General Physics and Astronomy
Reference21 articles.
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