PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF BACTERIAL ISOLATES CAUSING EAR INFECTION AMONG THE PATIENTS ATTENDING TERTIARY CARE HOSPITAL, PUDUCHERRY.

Abstract

Ear infection can cause pain, discharge, hearing impairement ,deafness and its related complications . Ear infection affects both children and adults particularly in developing countries. Since the emergence of antibiotic resistant organisms increasing the risk of treatment failure. The prevalence and susceptibility of isolates to antibiotics is important for patient treatment. The aim of the study to assess the prevalence of isolated bacterial pathogen and their antimicrobial susceptibility prole among patient with ear infection attended SLIMS , puducherry between Febuary 2021 – January 2022 . Materials And Methods: Retrospective data was collected for analysis from ear samples subjected for bacterial culture and antimicrobial susceptibility pattern . Specimens such as ear swabs and aspirated fuild was collected and processed for microbiological diagnosis as per standard operating procedure (SOP) .Antimicrobial susceptibility testing was performed according to Clinical and Laboratory Standard Institute (CLSI) guidelines. Statistical Package for the social sciences (SPSS) was used to analyzed the data . Results: Gram positive and gram negative organisms were isolated from 109 ear samples . Gram positive cocci accounted for 75 (68.8 %) and Gram negative bacilli for 34 (31.2 %) . Staphylococcus aureus (33%) and pseudomonas spp (21.1%) were the most commonly isolated organisms. In drug susceptibility testing, gentamicin had coverage against 68(90.7%) of 75 gram positive cocci and 30(88.2 %) of 34 gram negative bacilli which were tested. Antimicrobial resistance were observed for penicillin , Erythromycin ,clindamycin whereas ciprooxacin, gentamicin, chloramphenicol and cotrimoxazole were found to be susceptible against the isolated bacteria. Conclusion: The predominant isolate was Staphylococcus aureus and Pseudomonas spp. The antibiotic with the greatest bacterial coverage in drug susceptibility pattern was Gentamicin. Gentamicin showed good coverage against gram positive cocci and Gram negative bacilli isolated from ear infections. Ciprooxacin showed the lowest resistance rates to all bacterial isolates.