OCCURRENCE OF NON-FERMENTATIVE GRAM-NEGATIVE BACILLI AND THEIR DRUG RESISTANCE IN TERTIARY CARE RURAL HOSPITAL IN LONI, ( M.S.)

Abstract

Background: Aerobic non-fermenting Gram-negative bacilli (NF-GNB) once consider as a contaminant now associated with life-threatening infection and emerging as multi drug resistant nosocomial pathogens. Aim: Isolation and identication of NF-GNB in all the clinical samples and to determine antibiotic susceptibility pattern of the isolated NF-GNB. Materials And Methods: This study has been conducted in the Department of Microbiology at a tertiary care teaching hospital over a period of one year. NFGNB were isolated and identied from clinical samples by standard procedure and antibiotic sensitivity was performed (according to CLSI guidelines). Out of 1498 clinical specimens, 320 (21.36%) isolates were identied as NF-GNB. Maximu Results: m number of was blood, 90 (28.12%) followed by pus, 84 (26.25%), Pseudomonas Aeruginosa was the commonest isolate, 192 (60%), followed by Pseudomonas species, 58(18.12%) & Acinetobacter boumannii, 46(14.37%). All isolates most of them MDR and were sensitive to polymyxin B, colistin and tigecycline. Multi drug resistant NF-GNB was not uncommon in our hospital. All Conclusion: isolates were sensitive to polymyxin B, colistin and tigecycline. Indiscriminate use of antibiotics against these organisms should be avoided. It is necessary to identify NFGNB & to monitor their susceptibility pattern to guide the clinician for better care and management of patients.