EPITHELIOID GLIOBLASTOMA OF BRAIN: A RARE CASE REPORT WITH REVIEW OF LITERATURE

Abstract

A 52 year old female presented with complains of headache, dizziness and vomiting. Her MRI revealed a heterogenously enhancing tumor in right temporal lobe. She underwent gross total resection followed by chemoradiotherapy, but later succumbed to her illness. Histopathology showed highly pleomorphic tumor cells with eosinophillic cytoplasm and pleomorphic vesicular nuclei. A diagnosis of Epithelioid Glioblastoma was made. Epithelioid Glioblastoma is a rare pseudoepithelial form of glioblastoma. It usually presents in younger age group, is more malignant, difcult to differentiate from usual GBMs on radiology and needs aggressive management. No streamlined protocols exist for their diagnosis and treatment. The following communication discusses its epidemiology, pathology, diagnosis and management.