A RETROSPECTIVE OBSERVATIONAL STUDY TO DETERMINE ETIOLOGY IN PEDIATRIC PATIENTS WITH ACUTE LIVER FAILURE

Abstract

Acute liver failure is a less common disease in pediatrics. Its outcome mostly depends on the etiology. With known etiology the outcome is favourable and with advancement of liver transplantation, the mortality is further reduced. Most of the study for etiology are from western countries , study conducted at our center in attempt to know the prevailing etiology for acute hepatic failure in our region. Materials and method: Retrospective observational study was done at Pediatrics Department, Katihar medical college, Katihar, Bihar, over the period from September 2017 to December 2020. 62 cases were selected by reviewing the les which qualied the inclusion and exclusion criteria. Information was taken on self designed questionnniare. Result and discussion: Most common identiable etiology comes out Hepatitis A (9.6%) and Hepatitis B (9.6%) followed by bacterial infection (8.1%), drug induced hepatitis (3.2%) and wilson's disease (3.2%). There was 2 cases of HAV with coinfection of staphylococcus and salmonella each. Majority of cases (30 out of 62 cases) were nonA nonB nonC viral hepatitis.