EVALUATION OF EFFECT OF AQUEOUS EXTRACT OF PORTULACA OLERACEA LINN. LEAVES IN ACUTE INFLAMMATION-Reference-Cited by-同舟云学术

EVALUATION OF EFFECT OF AQUEOUS EXTRACT OF PORTULACA OLERACEA LINN. LEAVES IN ACUTE INFLAMMATION

Published:2020-10-01 Issue: Volume: Page:1-2
ISSN:
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
language:en
Short-container-title:ijsr

Author:

Medhabati M.¹,Babycha L.²,Tarinita L.¹,Tewari Bikram³,Sinha Saumya Kanti⁴

Affiliation:

1. Associate Professor, Department of Pharmacology, Regional Institute of Medical Sciences, Imphal, Manipur, India.

2. Associate Professor, Department of Pharmacology, Jawaharlal Institute of Medical Sciences, Imphal, Manipur, India.

3. Associate Professor, Department of Pharmacology Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.

4. Post graduate trainee, Department of Pharmacology, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Abstract

In the present study, the anti-inflammatory activity of aqueous extract of Portulaca oleracea (POE 200, 400 and 600mg/kg) was studied using carrageenan induced paw oedema in albino rats. The mean increase in paw volume was recorded. POE produced significant (p<,0.01) anti-inflammatory activity when compared to the control. The anti-inflammatory action of POEcan be attributed to its flavonoid contents which are known to act through inhibition of prostaglandin biosynthesis. However, the test drug at maximum dose (600mg/kg) was found to be less effective than the standard drug, aspirin (100mg/Kg).

Publisher

World Wide Journals

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